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Treatment-resistant schizophrenia: current insights on the pharmacogenomics of antipsychotics

Up to 30% of people with schizophrenia do not respond to two (or more) trials of dopaminergic antipsychotics. They are said to have treatment-resistant schizophrenia (TRS). Clozapine is still the only effective treatment for TRS, although it is underused in clinical practice. Initial use is delayed,...

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Detalhes bibliográficos
Publicado no:Pharmgenomics Pers Med
Main Authors: Lally, John, Gaughran, Fiona, Timms, Philip, Curran, Sarah R
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106233/
https://ncbi.nlm.nih.gov/pubmed/27853387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S115741
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