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Genetic variation rs7930 in the miR-4273-5p target site is associated with a risk of colorectal cancer

PURPOSE: MicroRNAs (miRNAs) are noncoding RNAs that play roles as tumor suppressors or oncogenes by regulating the expression of target genes via binding to seed-match sequences. Polymorphisms in the miRNA-binding site of a target gene can alter miRNA binding and potentially affect the risk of cance...

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Bibliografske podrobnosti
izdano v:Onco Targets Ther
Main Authors: Lee, Ah-Reum, Park, Jongkeun, Jung, Keum Ji, Jee, Sun Ha, Kim-Yoon, Sungjoo
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106228/
https://ncbi.nlm.nih.gov/pubmed/27853382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S108787
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