Green tea component epigallocatechin-3-gallate decreases expression of osteopontin via a decrease in mRNA half-life in cell lines of metastatic hepatocellular carcinoma

INTRODUCTION: Osteopontin (OPN) mediates metastasis and invasion of hepatocellular carcinoma (HCC). Epigallocatechin-3-gallate (EGCG), found in green tea, suppresses HCC tumor growth in vitro. We sought to investigate the role of EGCG in modulating OPN in cell lines of metastatic HCC. METHODS: Exper...

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Publicado no:Surgery
Main Authors: Zapf, Matthew A. C., Kothari, Anai N., Weber, Cynthia E., Arffa, Matthew L., Wai, Phillip Y., Driver, Joseph, Gupta, Gopal N., Kuo, Paul C., Mi, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105906/
https://ncbi.nlm.nih.gov/pubmed/26189955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2015.06.011
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