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The Fitness Effects of Spontaneous Mutations Nearly Unseen by Selection in a Bacterium with Multiple Chromosomes

Mutation accumulation (MA) experiments employ the strategy of minimizing the population size of evolving lineages to greatly reduce effects of selection on newly arising mutations. Thus, most mutations fix within MA lines independently of their fitness effects. This approach, more recently combined...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Dillon, Marcus M., Cooper, Vaughn S.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105853/
https://ncbi.nlm.nih.gov/pubmed/27672096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.193060
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