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Imperfect Symmetry of Sp1 and Core Promoter Sequences Regulates Early and Late Virus Gene Expression of the Bidirectional BK Polyomavirus Noncoding Control Region

Rearrangements or point mutations in the noncoding control region (NCCR) of BK polyomavirus (BKPyV) have been associated with higher viral loads and more pronounced organ pathology in immunocompromised patients. The respective alterations affect a multitude of transcription factor binding sites (TFB...

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Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Bethge, Tobias, Ajuh, Elvis, Hirsch, Hans H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105647/
https://ncbi.nlm.nih.gov/pubmed/27581987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01008-16
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