Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals

OBJECTIVE: Colorectal cancer (CRC) has a substantial heritable component. Common genetic variation has been shown to contribute to CRC risk. In a large, multi-population study, we set out to assess the feasibility of CRC risk prediction using common genetic variant data, combined with other risk fac...

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Bibliografiska uppgifter
I publikationen:Gut
Huvudupphovsmän: Dunlop, Malcolm G., Tenesa, Albert, Farrington, Susan M., Ballereau, Stephane, Brewster, David H., Pharoah, Paul DP., Schafmayer, Clemens, Hampe, Jochen, Völzke, Henry, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, von Holst, Susanna, Picelli, Simone, Lindblom, Annika, Jenkins, Mark A., Hopper, John L., Casey, Graham, Duggan, David, Newcomb, Polly, Abulí, Anna, Bessa, Xavier, Ruiz-Ponte, Clara, Castellví-Bel, Sergi, Niittymäki, Iina, Tuupanen, Sari, Karhu, Auli, Aaltonen, Lauri, Zanke, Brent W., Hudson, Thomas J., Gallinger, Steven, Barclay, Ella, Martin, Lynn, Gorman, Maggie, Carvajal-Carmona, Luis, Walther, Axel, Kerr, David, Lubbe, Steven, Broderick, Peter, Chandler, Ian, Pittman, Alan, Penegar, Steven, Campbell, Harry, Tomlinson, Ian, Houlston, Richard S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105590/
https://ncbi.nlm.nih.gov/pubmed/22490517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2011-300537
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