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Immunological and Translational Aspects of NK Cell-Based Antitumor Immunotherapies

Natural killer (NK) cells play a pivotal role in the first line of defense against cancer. NK cells that are deficient in CD3 and a clonal T cell receptor (TCR) can be subdivided into two major subtypes, CD56(dim)CD16(+) cytotoxic and CD56(bright)CD16(−) immunoregulatory NK cells. Cytotoxic NK cells...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Shevtsov, Maxim, Multhoff, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104957/
https://ncbi.nlm.nih.gov/pubmed/27891129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00492
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