Concentration-Dependent Dual Mode of Zn Action at Serotonin 5-HT1A Receptors: In Vitro and In Vivo Studies

Recent data has indicated that Zn can modulate serotonergic function through the 5-HT(1A) receptor (5-HT(1A)R); however, the exact mechanisms are unknown. In the present studies, radioligand binding assays and behavioural approaches were used to characterize the pharmacological profile of Zn at 5-HT...

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Pubblicato in:Mol Neurobiol
Autori principali: Satała, Grzegorz, Duszyńska, Beata, Stachowicz, Katarzyna, Rafalo, Anna, Pochwat, Bartlomiej, Luckhart, Christine, Albert, Paul R., Daigle, Mireille, Tanaka, Kenji F., Hen, René, Lenda, Tomasz, Nowak, Gabriel, Bojarski, Andrzej J., Szewczyk, Bernadeta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104769/
https://ncbi.nlm.nih.gov/pubmed/26660328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9586-3
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