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Evaluation of the contribution of the ATP binding cassette transporter, P-glycoprotein, to in vivo cholesterol homeostasis

P-glycoprotein (Pgp, encoded by ABCB1, commonly known as MDR1), an ATP-dependent transporter with a broad range of hydrophobic drug substrates, has been associated with the in vitro intracellular transport of cholesterol; however, these findings have not been confirmed in vivo. In this manuscript we...

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Detaylı Bibliyografya
Yayımlandı:Mol Pharm
Asıl Yazarlar: Lee, Stephen D., Thornton, Sheila J., Sachs-Barrable, Kristina, Kim, Jenny H., Wasan, Kishor M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104543/
https://ncbi.nlm.nih.gov/pubmed/23750858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4002415
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