Genome-Wide Scleral Micro- and Messenger-RNA Regulation During Myopia Development in the Mouse

PURPOSE: MicroRNA (miRNAs) have been previously implicated in scleral remodeling in normal eye growth. They have the potential to be therapeutic targets for prevention/retardation of exaggerated eye growth in myopia by modulating scleral matrix remodeling. To explore this potential, genome-wide miRN...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Metlapally, Ravikanth, Park, Han Na, Chakraborty, Ranjay, Wang, Kevin K., Tan, Christopher C., Light, Jacob G., Pardue, Machelle T., Wildsoet, Christine F.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2016
Fag:
Anatomy and Pathology/Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104419/
https://ncbi.nlm.nih.gov/pubmed/27832275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19563
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