Inhibition of PTTG1 expression by microRNA suppresses proliferation and induces apoptosis of malignant glioma cells

The present study aimed to investigate the role of pituitary tumor-transforming gene 1 (PTTG1) in the proliferation, invasion and apoptosis of human malignant glioma U251 cells. Firstly, 2 microRNAs (miRNAs) targeting PTTG1 messenger (m)RNA were ligated into a pcDNA6.2-GW/EmGFP-miR expression vector...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Su, Xing, Chen, Jianguo, Ni, Lanchun, Shi, Wei, Shi, Jinlong, Liu, Xiaojiang, Zhang, Yu, Gong, Peipei, Zhu, Hui, Huang, Qingfeng
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2016
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103968/
https://ncbi.nlm.nih.gov/pubmed/27900021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5035
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