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Heteroplasmy of mutant mitochondrial DNA A10398G and analysis of its prognostic value in non-small cell lung cancer

Mitochondrial dysfunction is associated with pathogenic mitochondrial (mt)DNA mutations. The majority of mtDNA point mutations have a heteroplasmic status, which is defined as the coexistence of wild-type and mutated DNA within a cell or tissue. Previous findings demonstrated that certain mtDNA hete...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Qi, Yuexiao, Wei, Yuehua, Wang, Qiaoli, Xu, Hui, Wang, You, Yao, Anqi, Yang, Hui, Gao, Yan, Zhou, Fuxiang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103904/
https://ncbi.nlm.nih.gov/pubmed/27899967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5086
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