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Oxymatrine inhibits microglia activation via HSP60-TLR4 signaling

Oxymatrine (OMT) is an alkaloid extracted from Sophora flavescens, which has broad anti-inflammatory, antitumor and immunosuppressant actions. However, the underlying molecular mechanisms have remained elusive. Heat shock protein 60 (HSP60) has recently been shown to have an important role in autoim...

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Bibliografiska uppgifter
I publikationen:Biomed Rep
Huvudupphovsmän: Ding, Feijia, Li, Yunhong, Hou, Xiaolin, Zhang, Rui, Hu, Shuting, Wang, Yin
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103688/
https://ncbi.nlm.nih.gov/pubmed/27882228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2016.776
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