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Tools for Model Building and Optimization into Near-Atomic Resolution Electron Cryo-Microscopy Density Maps

Electron cryo-microscopy (cryoEM) has advanced dramatically to become a viable tool for high-resolution structural biology research. The ultimate outcome of a cryoEM study is an atomic model of a macromolecule or its complex with interacting partners. This chapter describes a variety of algorithms a...

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Detalles Bibliográficos
Publicado en:Methods Enzymol
Autores principales: DiMaio, F., Chiu, W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103630/
https://ncbi.nlm.nih.gov/pubmed/27572730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2016.06.003
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