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AMITRIPTYLINE USAGE EXACERBATES THE IMMUNE SUPPRESSION FOLLOWING BURN INJURY

Currently, over 10% of the US population is taking antidepressants. Numerous antidepressants such as amitriptyline are known to inhibit acid sphingomyelinase (Asm), an enzyme that is known to mediate leukocyte function and homeostasis. Severe burn injury can lead to an immunosuppressive state that i...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Johnson, Bobby L., Rice, Teresa C., Xia, Brent T., Boone, Kirsten I., Green, Ellis A., Gulbins, Erich, Caldwell, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103308/
https://ncbi.nlm.nih.gov/pubmed/27172154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000648
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