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Marked increases in mucociliary clearance produced by synergistic secretory agonists or inhibition of the epithelial sodium channel

Mucociliary clearance (MCC) is a critical host innate defense mechanism in airways, and it is impaired in cystic fibrosis (CF) and other obstructive lung diseases. Epithelial fluid secretion and absorption modify MCC velocity (MCCV). We tested the hypotheses that inhibiting fluid absorption accelera...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Joo, Nam Soo, Jeong, Jin Hyeok, Cho, Hyung-Ju, Wine, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103292/
https://ncbi.nlm.nih.gov/pubmed/27830759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36806
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