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VEGF released by deferoxamine preconditioned mesenchymal stem cells seeded on collagen-GAG substrates enhances neovascularization

Hypoxia preconditioning of mesenchymal stem cells (MSCs) has been shown to promote wound healing through HIF-1α stabilization. Preconditioned MSCs can be applied to three-dimensional biomaterials to further enhance the regenerative properties. While environmentally induced hypoxia has proven difficu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wahl, Elizabeth A., Schenck, Thilo L., Machens, Hans-Günther, Balmayor, Elizabeth R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103276/
https://ncbi.nlm.nih.gov/pubmed/27830734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36879
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