The effect of an abuse‐deterrent opioid formulation (OxyContin) on opioid abuse‐related outcomes in the postmarketing setting

An extended‐release opioid analgesic (OxyContin, OC) was reformulated with abuse‐deterrent properties to deter abuse. This report examines changes in abuse through oral and nonoral routes, doctor‐shopping, and fatalities in 10 studies 3.5 years after reformulation. Changes in OC abuse from 1 year be...

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Vydáno v:Clin Pharmacol Ther
Hlavní autoři: Coplan, PM, Chilcoat, HD, Butler, SF, Sellers, EM, Kadakia, A, Harikrishnan, V, Haddox, JD, Dart, RC
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102571/
https://ncbi.nlm.nih.gov/pubmed/27170195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.390
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