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Upregulation of DAPK contributes to homocysteine-induced endothelial apoptosis via the modulation of Bcl2/Bax and activation of caspase 3

Hyperhomocysteinemia is characterized by an abnormally high level of homocysteine (Hcy) in the blood and is associated with cardiovascular diseases such as atherosclerosis. Endothelial dysfunction may lead to the pro-atherogenic effects associated with hyperhomocysteinemia. Endothelial dysfunction i...

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Bibliografski detalji
Izdano u:Mol Med Rep
Glavni autori: Tian, Xin, Shi, Yongfeng, Liu, Ning, Yan, Youyou, Li, Tianyi, Hua, Peiyan, Liu, Bin
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101913/
https://ncbi.nlm.nih.gov/pubmed/27633052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5733
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