PGC-1α modulates necrosis, inflammatory response, and fibrotic tissue formation in injured skeletal muscle

BACKGROUND: Skeletal muscle tissue has an enormous regenerative capacity that is instrumental for a successful defense against muscle injury and wasting. The peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) exerts therapeutic effects in several muscle pathologies, but its role in...

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Опубликовано в: :Skelet Muscle
Главные авторы: Dinulovic, Ivana, Furrer, Regula, Di Fulvio, Sabrina, Ferry, Arnaud, Beer, Markus, Handschin, Christoph
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101792/
https://ncbi.nlm.nih.gov/pubmed/27833743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-016-0110-x
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