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Resurrecting ancestral structural dynamics of an antiviral immune receptor: adaptive binding pocket reorganization repeatedly shifts RNA preference

BACKGROUND: Although resurrecting ancestral proteins is a powerful tool for understanding the molecular-functional evolution of gene families, nearly all studies have examined proteins functioning in relatively stable biological processes. The extent to which more dynamic systems obey the same ‘rule...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:BMC Evol Biol
Päätekijät: Pugh, Charles, Kolaczkowski, Oralia, Manny, Austin, Korithoski, Bryan, Kolaczkowski, Bryan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101713/
https://ncbi.nlm.nih.gov/pubmed/27825296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-016-0818-6
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