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Light Control of Insulin Release and Blood Glucose Using an Injectable Photoactivated Depot

[Image: see text] In this work we demonstrate that blood glucose can be controlled remotely through light stimulated release of insulin from an injected cutaneous depot. Human insulin was tethered to an insoluble but injectable polymer via a linker, which was based on the light cleavable di-methoxy...

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Vydáno v:Mol Pharm
Hlavní autoři: Sarode, Bhagyesh R., Kover, Karen, Tong, Pei Y., Zhang, Chaoying, Friedman, Simon H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2016
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101575/
https://ncbi.nlm.nih.gov/pubmed/27653828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00633
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