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Elevated Dopamine D(2/3) Receptor Availability in Obese Individuals: A PET Imaging Study with [(11)C](+)PHNO

Most prior work with positron emission tomography (PET) dopamine subtype 2/3 receptor (D(2/3)R) non-selective antagonist tracers suggests that obese (OB) individuals exhibit lower D(2/3)Rs when compared with normal weight (NW) individuals. A D(3)-preferring D(2/3)R agonist tracer, [(11)C](+)PHNO, ha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuropsychopharmacology
Hauptverfasser: Gaiser, Edward C, Gallezot, Jean-Dominique, Worhunsky, Patrick D, Jastreboff, Ania M, Pittman, Brian, Kantrovitz, Lauren, Angarita, Gustavo A, Cosgrove, Kelly P, Potenza, Marc N, Malison, Robert T, Carson, Richard E, Matuskey, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101552/
https://ncbi.nlm.nih.gov/pubmed/27374277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.115
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