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Effects of a PPAR -gamma receptor agonist and an angiotensin receptor antagonist on aortic contractile responses to alpha receptor agonists in diabetic and/or hypertensive rats

AIM: The aim of this study was to investigate the effects of pioglitazone and losartan pre-treatment on the aortic contractile response to the alpha-1 agonist, phenylephrine, and the alpha-2 agonist, clonidine, in L-NAME-induced hypertensive, STZ-induced diabetic, and hypertensive diabetic rats. MET...

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Détails bibliographiques
Publié dans:Cardiovasc J Afr
Auteurs principaux: Tugrul, Ibrahim, Dost, Turhan, Demir, Omer, Gokalp, Filiz, Oz, Ozlem, Girit, Necip, Birincioglu, Mustafa
Format: Artigo
Langue:Inglês
Publié: Clinics Cardive Publishing 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101471/
https://ncbi.nlm.nih.gov/pubmed/27149161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5830/CVJA-2015-080
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