Nucleosomes on linear duplex DNA allow homologous pairing but prevent strand exchange promoted by RecA protein.
To understand the molecular basis of gene targeting, we have studied interactions of nucleoprotein filaments comprised of single-stranded DNA and RecA protein with chromatin templates reconstituted from linear duplex DNA and histones. We observed that for the chromatin templates with histone/DNA mas...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1991
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1996335/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.4.1344 |
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