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The Oxidosqualene Cyclase from the Oomycete Saprolegnia parasitica Synthesizes Lanosterol as a Single Product

The first committed step of sterol biosynthesis is the cyclisation of 2,3-oxidosqualene to form either lanosterol (LA) or cycloartenol (CA). This is catalyzed by an oxidosqualene cyclase (OSC). LA and CA are subsequently converted into various sterols by a series of enzyme reactions. The specificity...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Dahlin, Paul, Srivastava, Vaibhav, Bulone, Vincent, McKee, Lauren S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101207/
https://ncbi.nlm.nih.gov/pubmed/27881978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01802
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