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IL-33 precedes IL-5 in regulating eosinophil commitment and is required for eosinophil homeostasis

Eosinophils are important in the pathogenesis of many diseases, including asthma, eosinophilic esophagitis, and eczema. While IL-5 is crucial for supporting mature eosinophils, the signals that support earlier eosinophil lineage events are less defined. The IL-33 receptor, ST2, is expressed on sever...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Johnston, Laura K, Hsu, Chia-Lin, Krier-Burris, Rebecca A, Chhiba, Krishan D, Chien, Karen B, McKenzie, Andrew, Berdnikovs, Sergejs, Bryce, Paul J
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101160/
https://ncbi.nlm.nih.gov/pubmed/27683753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600611
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