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IL-33 precedes IL-5 in regulating eosinophil commitment and is required for eosinophil homeostasis
Eosinophils are important in the pathogenesis of many diseases, including asthma, eosinophilic esophagitis, and eczema. While IL-5 is crucial for supporting mature eosinophils, the signals that support earlier eosinophil lineage events are less defined. The IL-33 receptor, ST2, is expressed on sever...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5101160/ https://ncbi.nlm.nih.gov/pubmed/27683753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600611 |
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