Skin Vaccination against Rotavirus Using Microneedles: Proof of Concept in Gnotobiotic Piglets

Live-attenuated oral rotavirus (RV) vaccines have lower efficacy in low income countries, and additionally are associated with a rare but severe adverse event, intussusception. We have been pursuing the development of an inactivated rotavirus vaccine (IRV) using the human rotavirus strain CDC-9 (G1P...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Wang, Yuhuan, Vlasova, Anastasia, Velasquez, Daniel E., Saif, Linda J., Kandasamy, Sukumar, Kochba, Efrat, Levin, Yotam, Jiang, Baoming
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100943/
https://ncbi.nlm.nih.gov/pubmed/27824918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166038
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