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Exploring Flexibility of Progesterone Receptor Ligand Binding Domain Using Molecular Dynamics
Progesterone receptor (PR), a member of nuclear receptor (NR) superfamily, plays a vital role for female reproductive tissue development, differentiation and maintenance. PR ligand, such as progesterone, induces conformation changes in PR ligand binding domain (LBD), thus mediates subsequent gene re...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5100906/ https://ncbi.nlm.nih.gov/pubmed/27824891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165824 |
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