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Generation of Mitochondrial-nuclear eXchange Mice via Pronuclear Transfer
The mitochondrial paradigm for common disease proposes that mitochondrial DNA (mtDNA) sequence variation can contribute to disease susceptibility and progression. To test this concept, we developed the Mitochondrial-nuclear eXchange (MNX) model, in which isolated embryonic pronuclei from one strain...
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| Publicado no: | Bio Protoc |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5100744/ https://ncbi.nlm.nih.gov/pubmed/27840835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.1976 |
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