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Identification of the mRNA targets of tRNA-specific regulation using genome-wide simulation of translation

tRNA gene copy number is a primary determinant of tRNA abundance and therefore the rate at which each tRNA delivers amino acids to the ribosome during translation. Low-abundance tRNAs decode rare codons slowly, but it is unclear which genes might be subject to tRNA-mediated regulation of expression....

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Gorgoni, Barbara, Ciandrini, Luca, McFarland, Matthew R., Romano, M. Carmen, Stansfield, Ian
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100601/
https://ncbi.nlm.nih.gov/pubmed/27407108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw630
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