Delta chirality ruthenium ‘light-switch’ complexes can bind in the minor groove of DNA with five different binding modes

[Ru(phen)(2)(dppz)](2+) has been studied since the 1990s due to its ‘light-switch’ properties. It can be used as a luminescent DNA probe, with emission switched on through DNA binding. The luminescence observed is dependent on the solvent accessibility of the pyrazine nitrogen atoms, and therefore i...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Hall, James P., Keane, Páraic M., Beer, Hanna, Buchner, Katrin, Winter, Graeme, Sorensen, Thomas L., Cardin, David J., Brazier, John A., Cardin, Christine J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Structural Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100598/
https://ncbi.nlm.nih.gov/pubmed/27599841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw753
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