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The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
GTP and branched-chain amino acids (BCAAs) are metabolic sensors that are indispensable for the determination of the metabolic status of cells. However, their molecular sensing mechanism remains unclear. CodY is a unique global transcription regulator that recognizes GTP and BCAAs as specific signal...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5100569/ https://ncbi.nlm.nih.gov/pubmed/27596595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw775 |
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