Phospho-site mutants of the RNA Polymerase II C-terminal domain alter subtelomeric gene expression and chromatin modification state in fission yeast

Eukaryotic gene expression requires that RNA Polymerase II (RNAP II) gain access to DNA in the context of chromatin. The C-terminal domain (CTD) of RNAP II recruits chromatin modifying enzymes to promoters, allowing for transcription initiation or repression. Specific CTD phosphorylation marks facil...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Inada, Maki, Nichols, Robert J., Parsa, Jahan-Yar, Homer, Christina M., Benn, Ruby A., Hoxie, Reyal S., Madhani, Hiten D., Shuman, Stewart, Schwer, Beate, Pleiss, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100562/
https://ncbi.nlm.nih.gov/pubmed/27402158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw603
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