Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients

BACKGROUND: CHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that chitinases are important in inflammatory processes and tissue remodeling, but the...

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Bibliographic Details
Published in:Clin Mol Allergy
Main Authors: Capone, Manuela, Maggi, Laura, Santarlasci, Veronica, Rossi, Maria Caterina, Mazzoni, Alessio, Montaini, Gianni, Cimaz, Rolando, Ramazzotti, Matteo, Piccinni, Marie Pierre, Barra, Giusi, De Palma, Raffaele, Liotta, Francesco, Maggi, Enrico, Romagnani, Sergio, Annunziato, Francesco, Cosmi, Lorenzo
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100333/
https://ncbi.nlm.nih.gov/pubmed/27826220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12948-016-0053-0
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