Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients

BACKGROUND: CHI3L1 is a chitinase-like protein without enzymatic activity, produced by activated macrophages, chondrocytes, neutrophils. Recent studies on arthritis, asthma, and inflammatory bowel diseases suggest that chitinases are important in inflammatory processes and tissue remodeling, but the...

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Опубликовано в: :Clin Mol Allergy
Главные авторы: Capone, Manuela, Maggi, Laura, Santarlasci, Veronica, Rossi, Maria Caterina, Mazzoni, Alessio, Montaini, Gianni, Cimaz, Rolando, Ramazzotti, Matteo, Piccinni, Marie Pierre, Barra, Giusi, De Palma, Raffaele, Liotta, Francesco, Maggi, Enrico, Romagnani, Sergio, Annunziato, Francesco, Cosmi, Lorenzo
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100333/
https://ncbi.nlm.nih.gov/pubmed/27826220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12948-016-0053-0
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