Hepatitis B virus X protein promotes interleukin-7 receptor expression via NF-κB and Notch1 pathway to facilitate proliferation and migration of hepatitis B virus-related hepatoma cells

BACKGROUND: Interleukin-7 receptor (IL-7R) is involved in the abnormal function of solid tumors, but the role and regulatory mechanisms of IL-7R in HBV-related hepatocellular carcinoma (HCC) are still unclear. METHODS: Gene and protein expression levels of IL-7R were examined in hepatoma cells trans...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Kong, Fanyun, Hu, Wei, Zhou, Kai, Wei, Xiao, Kou, Yanbo, You, Hongjuan, Zheng, Kuiyang, Tang, Renxian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100324/
https://ncbi.nlm.nih.gov/pubmed/27821177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0448-2
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