A new tool for the chemical genetic investigation of the Plasmodium falciparum Pfnek-2 NIMA-related kinase

BACKGROUND: Examining essential biochemical pathways in Plasmodium falciparum presents serious challenges, as standard molecular techniques such as siRNA cannot be employed in this organism, and generating gene knock-outs of essential proteins requires specialized conditional approaches. In the stud...

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Dettagli Bibliografici
Pubblicato in:Malar J
Autori principali: Mitcheson, Deborah F., Bottrill, Andrew R., Carr, Katherine, Coxon, Christopher R., Cano, Celine, Golding, Bernard T., Griffin, Roger J., Fry, Andrew M., Doerig, Christian, Bayliss, Richard, Tobin, Andrew B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Methodology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100313/
https://ncbi.nlm.nih.gov/pubmed/27821169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1580-3
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