Anthocyanins abrogate glutamate-induced AMPK activation, oxidative stress, neuroinflammation, and neurodegeneration in postnatal rat brain

BACKGROUND: Glutamate-induced excitotoxicity, oxidative damage, and neuroinflammation are believed to play an important role in the development of a number of CNS disorders. We recently reported that a high dose of glutamate could induce AMPK-mediated neurodegeneration in the postnatal day 7 (PND7)...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Shah, Shahid Ali, Amin, Faiz Ul, Khan, Mehtab, Abid, Muhammad Noman, Rehman, Shafiq Ur, Kim, Tae Hyun, Kim, Min Woo, Kim, Myeong Ok
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100309/
https://ncbi.nlm.nih.gov/pubmed/27821173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0752-y
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