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Mechanistic insights into mammalian stress granule dynamics

The accumulation of stalled translation preinitiation complexes (PICs) mediates the condensation of stress granules (SGs). Interactions between prion-related domains and intrinsically disordered protein regions found in SG-nucleating proteins promote the condensation of ribonucleoproteins into SGs....

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Panas, Marc D., Ivanov, Pavel, Anderson, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100297/
https://ncbi.nlm.nih.gov/pubmed/27821493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201609081
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