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Five factors can reconstitute all three phases of microtubule polymerization dynamics

Cytoplasmic microtubules (MTs) undergo growth, shrinkage, and pausing. However, how MT polymerization cycles are produced and spatiotemporally regulated at a molecular level is unclear, as the entire cycle has not been recapitulated in vitro with defined components. In this study, we reconstituted d...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Moriwaki, Takashi, Goshima, Gohta
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100292/
https://ncbi.nlm.nih.gov/pubmed/27799364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604118
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