Formin-generated actomyosin arcs propel T cell receptor microcluster movement at the immune synapse

Actin assembly and inward flow in the plane of the immunological synapse (IS) drives the centralization of T cell receptor microclusters (TCR MCs) and the integrin leukocyte functional antigen 1 (LFA-1). Using structured-illumination microscopy (SIM), we show that actin arcs populating the medial, l...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Murugesan, Sricharan, Hong, Jinsung, Yi, Jason, Li, Dong, Beach, Jordan R., Shao, Lin, Meinhardt, John, Madison, Grey, Wu, Xufeng, Betzig, Eric, Hammer, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100289/
https://ncbi.nlm.nih.gov/pubmed/27799367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603080
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