Comparative effectiveness of treatment with the first TNF antagonist in monotherapy, the first TNF antagonist plus one conventional synthetic disease-modifying antirheumatic drug, and the first TNF antagonist plus two or more conventional synthetic disease-modifying antirheumatic drugs in patients with rheumatoid arthritis

BACKGROUND: Rheumatoid arthritis (RA) patients are treated with a mean of 3–4 conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) with or without glucocorticoids (GCs), before the first biologic prescription. The main reasons for change are inefficacy in 30–40 % of patients, and...

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Dettagli Bibliografici
Pubblicato in:Arthritis Res Ther
Autori principali: Hernández-Cruz, Blanca, Márquez-Saavedra, Esther, Caliz-Caliz, Rafael, Navarro-Sarabia, Federico
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100281/
https://ncbi.nlm.nih.gov/pubmed/27821150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1137-4
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