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Retrovirus-induced spongiform myeloencephalopathy in mice: regional distribution of infected target cells and neuronal loss occurring in the absence of viral expression in neurons.

The Cas-Br-E murine leukemia virus (MuLV) induces a spongiform myeloencephalopathy resulting in a progressive hindlimb paralysis. We have used in situ hybridization with a Cas-Br-E MuLV-specific probe to study viral expression in the central nervous system. Infected cells were concentrated in region...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Kay, D G, Gravel, C, Robitaille, Y, Jolicoeur, P
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51001/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1847516/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.4.1281
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