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Nonhuman Primate Models for Evaluation of HIV-1 Preventative Vaccine Strategies: Model Parameter Considerations and Consequences

PURPOSE OF REVIEW: Nonhuman primate (NHP) models of AIDS are powerful systems for evaluating HIV vaccine approaches in vivo. Authentic features of HIV-1 transmission, dissemination, target cell tropism, and pathogenesis, and aspects of anti-HIV-1 immune responses, can be recapitulated in NHPs provid...

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Publicado en:Curr Opin HIV AIDS
Autores principales: Del Prete, Gregory Q., Lifson, Jeffrey D., Keele, Brandon F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100008/
https://ncbi.nlm.nih.gov/pubmed/27559710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0000000000000311
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