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Cucurbitacin E inhibits osteosarcoma cells proliferation and invasion through attenuation of PI3K/AKT/mTOR signalling pathway

Cucurbitacin E (CuE), a potent member of triterpenoid family isolated from plants, has been confirmed as an antitumour agent by inhibiting proliferation, migration and metastasis in diverse cancer. However, the effects and mechanisms of CuE on osteosarcoma (OS) have not been well understood. The pre...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Wang, Ying, Xu, Shumei, Wu, Yaochi, Zhang, Junfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100002/
https://ncbi.nlm.nih.gov/pubmed/27653525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160165
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