A prospective, multicentre, single-arm clinical trial of bevacizumab for patients with surgically untreatable, symptomatic brain radiation necrosis(†)

BACKGROUND: Brain radiation necrosis (BRN) can be a complication of radiotherapy for primary and secondary brain tumors, as well as head and neck tumors. Since vascular endothelial growth factor (VEGF) is also a vascular permeability factor in the brain, bevacizumab, a humanized antibody that inhibi...

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Detalhes bibliográficos
Publicado no:Neurooncol Pract
Main Authors: Furuse, Motomasa, Nonoguchi, Naosuke, Kuroiwa, Toshihiko, Miyamoto, Susumu, Arakawa, Yoshiki, Shinoda, Jun, Miwa, Kazuhiro, Iuchi, Toshihiko, Tsuboi, Koji, Houkin, Kiyohiro, Terasaka, Shunsuke, Tabei, Yusuke, Nakamura, Hideo, Nagane, Motoo, Sugiyama, Kazuhiko, Terasaki, Mizuhiko, Abe, Tatsuya, Narita, Yoshitaka, Saito, Nobuhito, Mukasa, Akitake, Ogasawara, Kuniaki, Beppu, Takaaki, Kumabe, Toshihiro, Nariai, Tadashi, Tsuyuguchi, Naohiro, Nakatani, Eiji, Kurisu, Shoko, Nakagawa, Yoko, Miyatake, Shin-Ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099992/
https://ncbi.nlm.nih.gov/pubmed/27833757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nop/npv064
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