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Real time monitoring of membrane GPCR reconstitution by plasmon waveguide resonance: on the role of lipids
G-protein coupled receptors (GPCRs) are important therapeutic targets since more than 40% of the drugs on the market exert their action through these proteins. To decipher the molecular mechanisms of activation and signaling, GPCRs often need to be isolated and reconstituted from a detergent-solubil...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5099921/ https://ncbi.nlm.nih.gov/pubmed/27824122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36181 |
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