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A smart hydrogel-based time bomb triggers drug release mediated by pH-jump reaction
We demonstrate a timed explosive drug release from smart pH-responsive hydrogels by utilizing a phototriggered spatial pH-jump reaction. A photoinitiated proton-releasing reaction of o-nitrobenzaldehyde (o-NBA) was integrated into poly(N-isopropylacrylamide-co-2-carboxyisopropylacrylamide) (P(NIPAAm...
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| Publicado no: | Sci Technol Adv Mater |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5099762/ https://ncbi.nlm.nih.gov/pubmed/27877529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1468-6996/13/6/064202 |
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