Intestinal Metrnl released into the gut lumen acts as a local regulator for gut antimicrobial peptides

AIM: Metrnl is a novel secreted protein, but its physiological roles remain elusive. In this study, we investigated the tissue expression pattern of Metrnl in humans and explored its possible physiological role in the tissues with most highly expressed levels. METHODS: A human tissue microarray cont...

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Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Li, Zhi-yong, Fan, Mao-bing, Zhang, Sai-long, Qu, Yi, Zheng, Si-li, Song, Jie, Miao, Chao-yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099411/
https://ncbi.nlm.nih.gov/pubmed/27546006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.70
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