Blockade of programmed death-1/programmed death ligand pathway enhances the antitumor immunity of human invariant natural killer T cells

The role of invariant natural killer T (iNKT) cells in antitumor immunity has been studied extensively, and clinical trials in patients with advanced cancer have revealed a prolonged survival in some cases. In recent years, humanized blocking antibodies against co-stimulatory molecules such as PD-1...

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Veröffentlicht in:Cancer Immunol Immunother
Hauptverfasser: Kamata, Toshiko, Suzuki, Akane, Mise, Naoko, Ihara, Fumie, Takami, Mariko, Makita, Yuji, Horinaka, Atsushi, Harada, Kazuaki, Kunii, Naoki, Yoshida, Shigetoshi, Yoshino, Ichiro, Nakayama, Toshinori, Motohashi, Shinichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099366/
https://ncbi.nlm.nih.gov/pubmed/27631416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1901-y
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